Gene mapping in experimental hypertension.
نویسندگان
چکیده
منابع مشابه
Genes and hypertension: from gene mapping in experimental models to vascular gene transfer strategies.
Human essential hypertension is a complex, multifactorial, quantitative trait under a polygenic control. Several strategies have been developed over the last decade to dissect genetic determinants of hypertension. Of these, the most successful have been studies that identified rare mendelian syndromes in which a single gene mutation causes high blood pressure. The attempts to identify multiple ...
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Hypertension is a multi-gene and multi-factorial disorder affecting about 25% of the population. Hypertensive subjects are more likely to develop other cardiovascular diseases such as peripheral vascular disease, coronary heart disease, congestive heart failure and cerebrovascular disease. To demonstrate potential therapeutic effects of somatic gene delivery in treating hypertension, we deliver...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 1992
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v3128